Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21122273 | 1.00 | DNM1 (0.42) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL5539894 | 0.95 | DNM1 (0.48) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL5544687 | 0.95 | DNM1 (0.48) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL5134448 | 0.95 | DNM1 (0.48) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL1728456 | 0.95 | DNM1 (0.48) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL28601890 | 0.95 | DNM1 (0.48) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL10674908 | 0.95 | DNM1 (0.48) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL5539887 | 0.95 | DNM1 (0.48) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL5544717 | 0.95 | DNM1 (0.48) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 | |
| SCHEMBL5540740 | 0.95 | DNM1 (0.48) | DNM1OPRM1PLA2G1BPLA2G2ASPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200115434-A1 | ANTIBODY/T-CELL RECEPTOR CHIMERIC CONSTRUCTS AND USES THEREOF | Eureka Therapeutics, Inc. | 2020-04-16 | — | — | US | disclosed |