Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1459570 | 0.85 | SLC7A5 (0.44) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL29002040 | 0.83 | HTR2A (0.44) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL11005389 | 0.83 | HTR2A (0.44) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL27633640 | 0.83 | HTR2A (0.44) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL8048483 | 0.83 | HTR2A (0.44) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL9168419 | 0.83 | HTR2A (0.44) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL3219880 | 0.83 | HTR2A (0.44) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL7448877 | 0.83 | HTR2A (0.44) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL16057441 | 0.83 | HTR2A (0.44) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 | |
| SCHEMBL7896297 | 0.83 | SLC7A5 (0.43) | SLC7A5SIGMAR1HTR2AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140206726-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-24 | — | — | US | claimed |
| EP-2748161-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-07-02 | — | — | EP | claimed |
| EP-2658853-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-11-06 | — | — | EP | claimed |
| US-20130289077-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-31 | — | — | US | claimed |
| WO-2013026836-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-28 | — | — | WO | claimed |
| US-20130012546-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-01-10 | — | — | US | claimed |
| EP-2519516-A2 | FUNGICIDAL HYDROXIMOYL-TETRAZOLE DERIVATIVES | Bayer CropScience AG (DE) | 2012-11-07 | — | — | EP | claimed |
| EP-2474542-A1 | Fungicide hydroximoyl-tetrazole derivatives | Bayer CropScience AG (DE) | 2012-07-11 | — | — | EP | claimed |
| WO-2012089757-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-07-05 | — | — | WO | claimed |
| WO-2011080255-A2 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | claimed |
| US-20140206726-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-07-24 | — | — | US | disclosed |
| EP-2748161-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2014-07-02 | — | — | EP | disclosed |
| EP-2658853-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | Bayer Intellectual Property GmbH (DE) | 2013-11-06 | — | — | EP | disclosed |
| US-20130289077-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-31 | — | — | US | disclosed |
| WO-2013026836-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-02-28 | — | — | WO | disclosed |
| US-20130012546-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2013-01-10 | — | — | US | disclosed |
| EP-2519516-A2 | FUNGICIDAL HYDROXIMOYL-TETRAZOLE DERIVATIVES | Bayer CropScience AG (DE) | 2012-11-07 | — | — | EP | disclosed |
| EP-2474542-A1 | Fungicide hydroximoyl-tetrazole derivatives | Bayer CropScience AG (DE) | 2012-07-11 | — | — | EP | disclosed |
| WO-2012089757-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-07-05 | — | — | WO | disclosed |
| WO-2011080255-A2 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289077-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | CYP4X1, HPD, CYP8B1 | SLC7A5 3673/4885SIGMAR1 4174/4885HTR2A 2403/4885 |
| US-20140206726-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | HPD, HAAO, CYP8B1 | SLC7A5 3079/4885SIGMAR1 4391/4885HTR2A 3170/4885 |
| US-20130012546-A1 | FUNGICIDE HYDROXIMOYL-TETRAZOLE DERIVATIVES | HPD, HAAO, CYP8B1 | SLC7A5 3079/4885SIGMAR1 4391/4885HTR2A 3170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.