Acetic Acid

Acetic Acid

SCHEMBL2194343

C1=Cc2ccccc2OC1.CC(=O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2B6 P20813 3/20 0.40
ALOX5 P09917 1/20 0.40
STS P08842 1/20 0.39
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
NOTUM Q6P988 1/20 0.36
CYP1A1 P04798 6/20 0.35
CYP1A2 P05177 6/20 0.35
CYP1B1 Q16678 4/20 0.35
HSD17B3 P37058 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL11766141 0.98 CYP2B6 (0.39) CYP2B6ALOX5STSGAASMN1; SMN2
Acetic Acid SCHEMBL10486832 0.95 CYP2B6 (0.37) CYP2B6ALOX5STSGAASMN1; SMN2
Bicarbonate SCHEMBL2467502 0.93 CYP2B6 (0.41) CYP2B6ALOX5STSGAASMN1; SMN2
Bicarbonate SCHEMBL4853459 0.93 CYP2B6 (0.41) CYP2B6ALOX5STSGAASMN1; SMN2
Acetamide SCHEMBL7696551 0.91 STS (0.41) CYP2B6ALOX5STSGAASMN1; SMN2
Bicarbonate SCHEMBL8638184 0.91 CYP2B6 (0.40) CYP2B6ALOX5STSGAASMN1; SMN2
Hydrogen Peroxide SCHEMBL15163598 0.91 CYP2B6 (0.41) CYP2B6ALOX5STSSMN1; SMN2CYP1A1
Methacrylic Acid SCHEMBL6279478 0.90 CYP2B6 (0.36) CYP2B6ALOX5STSGAASMN1; SMN2
Carbamic Acid SCHEMBL19873345 0.89 STS (0.42) CYP2B6ALOX5STSGAACYP1A1
Methyl Alcohol SCHEMBL7362937 0.89 CYP2B6 (0.40) CYP2B6ALOX5STSGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105150549-B The manufacture method of polychrome acetate fiber glasses frame 王道敏 2017-07-04 CN claimed
CN-105150549-A Multi-colour cellulose acetate fiber spectacle frame manufacturing method WANG DAOMIN 2015-12-16 CN claimed
US-7157072-B2 Cathode composition for lithium batteries and method of preparing the same ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2007-01-02 US claimed
US-20050069772-A1 Cathode composition for lithium batteries and method of preparing the same INTELLECTUAL DISCOVERY CO., LTD. (KR) 2005-03-31 US claimed
US-20040224853-A1 Drilling fluid additives JASINSKI RICARDO (AR) 2004-11-11 US claimed
US-4505825-A BORON-CHROME-LIGONOSULFONATE REED LIGNIN INC. (US) 1985-03-19 US claimed
US-11981864-B1 Temporary isolation system for reservoirs BAKER HUGHES OILFIELD OPERATIONS LLC (US) 2024-05-14 US disclosed
US-11834594-B2 Methods for drilling wellbores using thinner compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-12-05 US disclosed
CN-114792770-A Display panel and display device 武汉天马微电子有限公司 2022-07-26 CN disclosed
EP-3953431-A1 METHODS FOR DRILLING WELLBORES USING THINNER COMPOSITIONS Chevron Phillips Chemical Company LP (US) 2022-02-16 EP disclosed
US-20210388253-A1 Methods for Drilling Wellbores Using Thinner Compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2021-12-16 US disclosed
WO-2020210294-A1 METHODS FOR DRILLING WELLBORES USING THINNER COMPOSITIONS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-10-15 WO disclosed
US-20200325380-A1 Methods for Drilling Wellbores Using Thinner Compositions CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2020-10-15 US disclosed
US-4421847-A ACTIVATION OF CARBOXYL GROUPS, PHOTOGRAPHIC FILMS AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1983-12-20 US disclosed
US-4308345-A CYANINE DYES FOR COLOR FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US disclosed
US-4248963-A BY BACK COATING WITH AN AQUEOUS DISPERSION OF ANIONIC EMULSIFIER AND ACRYLIC-VINYL COPOLYMERS AGFA-GEVAERT, A.G. (DE) 1981-02-03 US disclosed
US-4216290-A Coating of viscous aqueous gelatin compositions on a continuous web support AGFA-GEVAERT N.V. (BE) 1980-08-05 US disclosed
US-4097284-A TRIMETHINECYANINE DYE AND A NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING A MERCAPTO FUJI PHOTO FILM CO., LTD. (JA) 1978-06-27 US disclosed
US-3984247-A Dye-containing silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-10-05 US disclosed
US-3966472-A SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JA) 1976-06-29 US disclosed