Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18686883 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A | |
| SCHEMBL18716411 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A | |
| SCHEMBL23192345 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A | |
| SCHEMBL18716410 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A | |
| SCHEMBL4184525 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A | |
| SCHEMBL19807111 | 0.78 | HSD11B1 (0.43) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A | |
| SCHEMBL19444202 | 0.78 | HSD11B1 (0.43) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A | |
| SCHEMBL9368238 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A | |
| SCHEMBL18686886 | 0.76 | HSD11B1 (0.42) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A | |
| SCHEMBL18716413 | 0.76 | HSD11B1 (0.42) | SMN1; SMN2HSD11B1NPSR1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150581-B1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2020-04-15 | — | — | EP | disclosed |