Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 16/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17303860 | 1.00 | LNPEP (0.52) | LNPEPOPRK1KCNH2OPRM1 | |
| SCHEMBL21944976 | 1.00 | LNPEP (0.52) | LNPEPOPRK1KCNH2OPRM1 | |
| SCHEMBL17303644 | 0.84 | LNPEP (0.49) | LNPEPOPRK1KCNH2 | |
| SCHEMBL18716503 | 0.84 | LNPEP (0.49) | LNPEPOPRK1KCNH2 | |
| SCHEMBL21944433 | 0.84 | LNPEP (0.49) | LNPEPOPRK1KCNH2 | |
| SCHEMBL23554564 | 0.81 | LNPEP (0.38) | LNPEP | |
| SCHEMBL13802796 | 0.81 | LNPEP (0.52) | LNPEP | |
| SCHEMBL18686910 | 0.79 | LNPEP (0.54) | LNPEPOPRK1KCNH2 | |
| SCHEMBL17303876 | 0.79 | LNPEP (0.53) | LNPEP | |
| SCHEMBL17303863 | 0.79 | LNPEP (0.55) | LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150581-B1 | PYRIDINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2020-04-15 | — | — | EP | disclosed |