⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428713 | 0.75 | — | — | |
| SCHEMBL12654071 | 0.75 | — | — | |
| SCHEMBL29374623 | 0.75 | — | — | |
| SCHEMBL17964073 | 0.75 | — | — | |
| SCHEMBL47044 | 0.75 | — | — | |
| SCHEMBL30790426 | 0.75 | — | — | |
| SCHEMBL31607680 | 0.75 | — | — | |
| SCHEMBL2298700 | 0.73 | — | — | |
| SCHEMBL30955009 | 0.73 | HDAC4 (0.36) | — | |
| SCHEMBL21118379 | 0.73 | LMNA (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102977010-A | Preparation method of 2-[4-(5-chloro-3-fluoro-2-pyridyloxy)phenoxy]propionate | UNIV TAIZHOU | 2013-03-20 | — | — | CN | claimed |
| US-20220402910-A1 | THIADIAZOLE IRAK4 INHIBITORS | GILEAD SCIENCES, INC. | 2022-12-22 | — | — | US | disclosed |
| WO-2020210139-A1 | PYRAZOLESULFONAMIDES AS ANTITUMOR AGENTS | PELOTON THERAPEUTICS, INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| EP-2794593-B1 | SPIRO AMINIC COMPOUNDS AS OREXIN ANTAGONISTS | Rottapharm Biotech Srl (IT) | 2017-02-01 | — | — | EP | disclosed |
| US-8993598-B2 | Pyrrole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8969387-B2 | Pyrrole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-03-03 | — | — | US | disclosed |
| CN-102977010-B | Preparation method of 2-[4-(5-chloro-3-fluoro-2-pyridyloxy)phenoxy]propionate | UNIV TAIZHOU | 2014-05-28 | — | — | CN | disclosed |
| US-20140031393-A1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-01-30 | — | — | US | disclosed |
| US-8592597-B2 | Pyrrole compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-11-26 | — | — | US | disclosed |
| EP-2318390-B1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL (JP) | 2013-05-01 | — | — | EP | disclosed |
| CN-102977010-A | Preparation method of 2-[4-(5-chloro-3-fluoro-2-pyridyloxy)phenoxy]propionate | UNIV TAIZHOU | 2013-03-20 | — | — | CN | disclosed |
| CN-102977010-A | Preparation method of 2-[4-(5-chloro-3-fluoro-2-pyridyloxy)phenoxy]propionate | UNIV TAIZHOU | 2013-03-20 | — | — | CN | disclosed |
| CN-102197033-A | Pyrrole compounds | TAKEDA PHARMACEUTICAL | 2011-09-21 | — | — | CN | disclosed |
| US-20110172275-A1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20100056577-A1 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | US | disclosed |