SCHEMBL219478

SCHEMBL219478

CC(=O)Nc1nc2nc[nH]c2c(=O)[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 1/20 1.00
XDH P47989 3/20 0.57
KDM4E B2RXH2 1/20 0.55
GAA P10253 1/20 0.55
FGFR1 P11362 1/20 0.54
FGFR2 P21802 1/20 0.54
PNP P00491 1/20 0.51
POLA1 P09884 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9581457 0.94 GDA (0.89) GDAXDHKDM4EGAAFGFR1
2-Pyrrolidone SCHEMBL9219915 0.87 GDA (0.75) GDAXDHKDM4EGAAFGFR1
SCHEMBL19466100 0.87 GDA (0.76) GDAXDHPNPPOLA1
SCHEMBL29411658 0.86 GDA (0.76) GDAXDHPNPPOLA1
SCHEMBL28559767 0.86 GDA (0.75) GDAXDHPNPPOLA1
SCHEMBL31093422 0.85 GDA (0.74) GDAXDHPNPPOLA1
SCHEMBL6821775 0.85 GDA (0.74) GDAXDHPNPPOLA1
SCHEMBL30510976 0.85 GDA (0.74) GDAXDHPNPPOLA1
SCHEMBL735411 0.84 GDA (0.72) GDAXDHPNP
SCHEMBL1965519 0.84 GDA (0.71) GDAXDHPOLA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114047262-B Method for separating and measuring easily-hydrolyzed large polar compound 湖北省宏源药业科技股份有限公司 2024-12-13 CN claimed
CN-115367745-B Tungsten-containing substance hybridization and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2023-11-24 CN claimed
CN-115367726-A Oxygen-doped titanium nitride hybridized and nitrogen-doped porous carbon material and preparation method and application thereof 北京化工大学 2022-11-22 CN claimed
CN-115367745-A Tungsten-containing substance hybrid and nitrogen-doped porous carbon material and preparation method thereof 北京化工大学 2022-11-22 CN claimed
CN-114047262-A Method for separating and measuring easily hydrolyzed large-polarity compound 湖北省宏源药业科技股份有限公司 2022-02-15 CN claimed
CN-113735857-A Acyclovir potential impurity and preparation method thereof 湖北省宏源药业科技股份有限公司 2021-12-03 CN claimed
WO-2021238912-A1 TRANSITION METAL COMPOUND-HYBRIDIZED AND NITROGEN-DOPED POROUS CARBON MATERIAL AND PREPARATION METHOD THEREFOR 北京化工大学 2021-12-02 WO claimed
CN-111892047-A Vanadium nitride hybrid and nitrogen-doped porous carbon material and preparation method and application thereof 北京化工大学 2020-11-06 CN claimed
CN-107074911-B Peptide nucleic acid monomers and oligomers 优基艾森斯股份公司 2020-11-03 CN claimed
CN-108467396-A A kind of preparation method of Ganciclovir 安徽海康药业有限责任公司 2018-08-31 CN claimed
EP-1453833-A2 A PROCESS FOR THE PREPARATION OF GANCICLOVIR INTERMEDIATE N2-ACETYL-9-(1,3-DIACETOXY-2-PROPOXYMETHYL) GUANINE RANBAXY LABORATORIES, LTD. (IN) 2004-09-08 EP claimed
US-20030198656-A1 N-acetylamino acids, related N-acetyl compounds and their topical use YU RUEY J (US) 2003-10-23 US claimed
WO-2003033498-A2 A PROCESS FOR THE TREATMENT OF GANCICLOVIR INTERMEDIATE N2-ACETYL-9-(1, 3-DIACETOXY-2-PROPOXYMETHYL) GUANINE RANBAXY LABORATORIES LIMITED (IN) 2003-04-24 WO claimed
US-5780607-A PYRANOSYL NUCLEOSIDE MONOMER UNITS CONNECTED BY AMIDE LINKAGES HOFFMANN-LA ROCHE INC. (US) 1998-07-14 US claimed
WO-1997014709-A1 ANTISENSE OLIGOMERS F. HOFFMANN-LA ROCHE AG (CH) 1997-04-24 WO claimed
WO-1997011944-A1 IMPROVED PROCESS FOR PRODUCING 9-(2-HYDROXYETHOXY)-METHYLGUANINE (ACYCLOVIR) BOEHRINGER INGELHEIM KG (DE) 1997-04-03 WO claimed
CN-1128269-A Oligoribonucleotides with amide backbone HOFFMANN LA ROCHE (CH) 1996-08-07 CN claimed
EP-0714907-A1 Oligoribonucleotides with amide backbone F. HOFFMANN-LA ROCHE AG (CH) 1996-06-05 EP claimed
WO-1992011276-A1 NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1992-07-09 WO claimed
EP-0049072-A1 Guanine compounds and their use for the preparation of anti-viral agents SYNTEX (U.S.A.) INC. (US) 1982-04-07 EP claimed