Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | RET | P07949 | 3/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | ROS1 | P08922 | 2/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.47 |
| ▸ | CLK2 | P49760 | 2/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17962768 | 0.88 | RET (0.53) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL17962836 | 0.86 | PRKD3 (0.54) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL17962793 | 0.84 | KCNH2 (0.48) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL868744 | 0.83 | PIK3CD (0.51) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL17963689 | 0.80 | RET (0.46) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL4572201 | 0.80 | RET (0.48) | MAPK1RETDYRK3CDK1ROS1 | |
| SCHEMBL17962785 | 0.79 | FYN (0.49) | MAPK1RETDYRK3CDK1ROS1 | |
| SCHEMBL17936088 | 0.79 | MAPK1 (0.47) | MAPK1CYP1A2KDM4ETP53CYP3A4 | |
| SCHEMBL16701523 | 0.78 | ADK (0.49) | MAPK1RETDYRK3CDK1ROS1 | |
| SCHEMBL21293809 | 0.78 | ADORA2A (0.48) | MAPK1RETDYRK3CDK1ROS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10632122-B2 | Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases | UNIVERSITY OF WASHINGTON (US) | 2020-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10632122-B2 | Compositions and methods for treating toxoplasmosis, cryptosporidiosis and other apicomplexan protozoan related diseases | PNCK, TXK, CAMKK1 | MAPK1 678/4885CYP1A2 2735/4885KDM4E 2532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.