Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21837400 | 0.84 | FOLH1 (0.47) | FOLH1CTSGCMA1ALDH1A1KMT2A | |
| SCHEMBL21837402 | 0.84 | FOLH1 (0.47) | FOLH1CTSGCMA1ALDH1A1KMT2A | |
| SCHEMBL21837393 | 0.82 | TAAR1 (0.51) | FOLH1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL21837394 | 0.82 | TAAR1 (0.51) | FOLH1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4060569 | 0.82 | POLB (0.52) | FOLH1ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL21950787 | 0.81 | FOLH1 (0.47) | FOLH1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4958129 | 0.79 | CTSL (0.62) | FOLH1ALDH1A1 | |
| SCHEMBL31407513 | 0.79 | CTSL (0.62) | FOLH1ALDH1A1 | |
| SCHEMBL18228830 | 0.79 | ACE (0.54) | CTSGCMA1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL18228922 | 0.79 | ACE (0.54) | CTSGCMA1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131669-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131669-A1 | CYCLIC PEPTIDE COMPOUND HAVING HIGH MEMBRANE PERMEABILITY, AND LIBRARY CONTAINING SAME | VIP, SLC7A1, TRPV1 | FOLH1 1020/4885CHRNB2 3094/4885CHRNB4 2787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.