Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.59 |
| ▸ | CTSK | P43235 | 5/20 | 0.59 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | CTSL | P07711 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 5/20 | 0.53 |
| ▸ | PLAU | P00749 | 5/20 | 0.53 |
| ▸ | PLAT | P00750 | 5/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 4/20 | 0.51 |
| ▸ | REN | P00797 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21950823 | 0.85 | PLAU (0.57) | F2PLAUPLATPLG | |
| SCHEMBL11126448 | 0.81 | BCL2 (0.59) | CTSSCTSKCTSBCTSLHDAC8 | |
| SCHEMBL29484189 | 0.80 | ACE (0.72) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL10050068 | 0.80 | ACE (0.72) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL30688549 | 0.80 | ACE (0.72) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL2367371 | 0.80 | ACE (0.72) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL9551322 | 0.80 | ACE (0.72) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL21219305 | 0.80 | ACE (0.72) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL15671562 | 0.80 | ACE (0.72) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL16999951 | 0.80 | CTSS (0.71) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653215-A1 | THERANOSTIC INHIBITORS AND ACTIVITY-BASED PROBES FOR THE KLK7 PROTEASE | University of Patras (GR) | 2020-05-20 | — | — | EP | claimed |
| EP-3653215-A1 | THERANOSTIC INHIBITORS AND ACTIVITY-BASED PROBES FOR THE KLK7 PROTEASE | University of Patras (GR) | 2020-05-20 | — | — | EP | disclosed |