Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 12/20 | 0.45 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196390 | 0.87 | GCK (0.49) | GCK | |
| SCHEMBL1959747 | 0.81 | GCK (0.58) | GCK | |
| SCHEMBL1959745 | 0.81 | GCK (0.58) | GCK | |
| SCHEMBL1964344 | 0.76 | HDAC6 (0.39) | GCKEPHX2EGLN1 | |
| SCHEMBL1960807 | 0.76 | GCK (0.57) | GCKATR | |
| SCHEMBL1961027 | 0.76 | GCK (0.57) | GCKATR | |
| SCHEMBL1961944 | 0.75 | GCK (0.55) | GCK | |
| SCHEMBL1960236 | 0.74 | GCK (0.56) | GCKEPHX2 | |
| SCHEMBL1963036 | 0.74 | GCK (0.56) | GCKEPHX2 | |
| SCHEMBL1962540 | 0.73 | GCK (0.56) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |