Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195183 | 0.87 | GCK (0.45) | GCK | |
| SCHEMBL1959747 | 0.67 | GCK (0.58) | GCKKCNH2 | |
| SCHEMBL1959745 | 0.67 | GCK (0.58) | GCKKCNH2 | |
| SCHEMBL22672733 | 0.67 | HDAC6 (0.46) | HDAC6 | |
| SCHEMBL2197922 | 0.66 | GCK (0.50) | GCK | |
| SCHEMBL1960462 | 0.64 | GCK (0.50) | GCKKCNH2 | |
| SCHEMBL2060154 | 0.63 | KDM5A (0.43) | — | |
| SCHEMBL19029353 | 0.63 | HDAC6 (0.78) | HDAC6 | |
| SCHEMBL4946467 | 0.61 | IP6K1 (0.48) | CNR1HDAC6CNR2 | |
| SCHEMBL411076 | 0.61 | CNR1 (0.67) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | claimed |
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |