⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724790 | 0.81 | KMT2A (0.30) | — | |
| SCHEMBL20696689 | 0.80 | — | — | |
| SCHEMBL15238228 | 0.80 | STK17B (0.39) | — | |
| SCHEMBL29437369 | 0.80 | STK17B (0.39) | — | |
| SCHEMBL28075627 | 0.80 | — | — | |
| SCHEMBL19301819 | 0.77 | — | — | |
| SCHEMBL18493964 | 0.76 | — | — | |
| SCHEMBL20913346 | 0.75 | — | — | |
| SCHEMBL4200625 | 0.73 | KDM4E (0.31) | — | |
| SCHEMBL28294701 | 0.73 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653209-A1 | TRANSIENT PROTECTION OF NORMAL CELLS DURING CHEMOTHERAPY | G1 Therapeutics, Inc. (US) | 2020-05-20 | — | — | EP | disclosed |