Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075627 | 0.74 | — | — | |
| SCHEMBL18546635 | 0.72 | STK17B (0.31) | — | |
| SCHEMBL16058177 | 0.70 | PIK3CD (0.34) | MAPT | |
| SCHEMBL28227350 | 0.69 | — | — | |
| SCHEMBL4201277 | 0.66 | CCR9 (0.36) | — | |
| SCHEMBL25857099 | 0.66 | HCAR1 (0.31) | — | |
| SCHEMBL28174161 | 0.65 | — | — | |
| SCHEMBL28175196 | 0.65 | — | — | |
| SCHEMBL4196176 | 0.61 | ENPP2 (0.39) | — | |
| SCHEMBL4189802 | 0.60 | SIK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109789143-A | Antiproliferative based on pyrimidine | G1治疗公司 | 2019-05-21 | — | — | CN | disclosed |