Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 6/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22434648 | 0.91 | HSP90AB1 (0.46) | HSP90AB1CYP19A1MAOB | |
| SCHEMBL21954710 | 0.85 | HSP90AB1 (0.44) | HSP90AB1CYP19A1MAOB | |
| SCHEMBL22404387 | 0.85 | HSP90AB1 (0.44) | HSP90AB1CYP19A1MAOB | |
| SCHEMBL28683976 | 0.78 | HSP90AB1 (0.45) | HSP90AB1 | |
| SCHEMBL14230307 | 0.77 | CYP19A1 (0.38) | CYP19A1 | |
| SCHEMBL20615467 | 0.75 | POLB (0.41) | CYP19A1 | |
| SCHEMBL22351908 | 0.75 | HSP90AB1 (0.50) | HSP90AB1CYP19A1MAOB | |
| SCHEMBL10299506 | 0.74 | CYP19A1 (0.54) | CYP19A1 | |
| SCHEMBL18618632 | 0.74 | CYP19A1 (0.54) | CYP19A1 | |
| SCHEMBL25109460 | 0.74 | CYP19A1 (0.44) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2021-05-20 | — | — | US | disclosed |
| US-10919937-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2021-02-16 | — | — | US | disclosed |
| US-10857196-B2 | Bicyclic peptide ligands and uses thereof | BICYCLETX LIMITED (GB) | 2020-12-08 | — | — | US | disclosed |
| US-20200131228-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10857196-B2 | Bicyclic peptide ligands and uses thereof | VIP, NGLY1, BID | HSP90AB1 2791/4885CYP19A1 2220/4885MAOB 4000/4885 |
| US-20200131228-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | HSP90AB1 2791/4885CYP19A1 2220/4885MAOB 4000/4885 |
| US-20210147484-A1 | BICYCLIC PEPTIDE LIGANDS AND USES THEREOF | VIP, NGLY1, BID | HSP90AB1 2791/4885CYP19A1 2220/4885MAOB 4000/4885 |
| US-10919937-B2 | Bicyclic peptide ligands and uses thereof | VIP, NGLY1, BID | HSP90AB1 2791/4885CYP19A1 2220/4885MAOB 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.