Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.39 |
| ▸ | NEU4 | Q8WWR8 | 1/20 | 0.38 |
| ▸ | NEU3 | Q9UQ49 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713570 | 0.85 | POLB (0.43) | POLBKMT2ACYP19A1NEU4NEU3 | |
| SCHEMBL10299506 | 0.83 | CYP19A1 (0.54) | CYP19A1HRH4HRH3GGPS1GBA1 | |
| SCHEMBL13359255 | 0.79 | POLB (0.47) | POLBKMT2ACYP19A1HRH4HRH3 | |
| SCHEMBL25109460 | 0.79 | CYP19A1 (0.44) | CYP19A1HRH4HRH3GGPS1GBA1 | |
| SCHEMBL4962353 | 0.78 | POLB (0.39) | POLBKMT2ACYP19A1NEU4NEU3 | |
| SCHEMBL25109369 | 0.77 | CYP19A1 (0.39) | CYP19A1HRH4HRH3GGPS1L3MBTL1 | |
| SCHEMBL22062687 | 0.76 | HRH4 (0.47) | POLBKMT2ACYP19A1HRH4HRH3 | |
| SCHEMBL21954703 | 0.75 | HSP90AB1 (0.40) | CYP19A1 | |
| SCHEMBL24352447 | 0.75 | RAD52 (0.31) | GGPS1 | |
| SCHEMBL19956575 | 0.74 | TSHR (0.39) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10676467-B2 | Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof | WASHINGTON UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-20190002450-A1 | COMPOSITIONS FOR BINDING SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1P1), IMAGING OF S1P1, AND METHODS OF USE THEREOF | WASHINGTON UNIVERSITY (US) | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002450-A1 | COMPOSITIONS FOR BINDING SPHINGOSINE-1-PHOSPHATE RECEPTOR 1 (S1P1), IMAGING OF S1P1, AND METHODS OF USE THEREOF | S1PR1, S1PR2, S1PR3 | POLB 3855/4885KMT2A 4416/4885CYP19A1 4667/4885 |
| US-10676467-B2 | Compositions for binding sphingosine-1-phosphate receptor 1 (S1P1), imaging of S1P1, and methods of use thereof | S1PR1, S1PR2, S1PR3 | POLB 3855/4885KMT2A 4416/4885CYP19A1 4667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.