Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 16/20 | 0.63 |
| ▸ | LONP1 | P36776 | 11/20 | 0.63 |
| ▸ | PSMB8 | P28062 | 11/20 | 0.63 |
| ▸ | PSMB9 | P28065 | 11/20 | 0.63 |
| ▸ | PSMB6 | P28072 | 11/20 | 0.63 |
| ▸ | PSMB10 | P40306 | 11/20 | 0.63 |
| ▸ | PSMB11 | A5LHX3 | 10/20 | 0.63 |
| ▸ | PSMA7 | O14818 | 10/20 | 0.63 |
| ▸ | PSMB1 | P20618 | 10/20 | 0.63 |
| ▸ | PSMA1 | P25786 | 10/20 | 0.63 |
| ▸ | PSMA2 | P25787 | 10/20 | 0.63 |
| ▸ | PSMA3 | P25788 | 10/20 | 0.63 |
| ▸ | PSMA4 | P25789 | 10/20 | 0.63 |
| ▸ | PSMA5 | P28066 | 10/20 | 0.63 |
| ▸ | PSMB4 | P28070 | 10/20 | 0.63 |
| ▸ | PSMB3 | P49720 | 10/20 | 0.63 |
| ▸ | PSMB2 | P49721 | 10/20 | 0.63 |
| ▸ | PSMA6 | P60900 | 10/20 | 0.63 |
| ▸ | PSMA8 | Q8TAA3 | 10/20 | 0.63 |
| ▸ | PSMB7 | Q99436 | 10/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL1041561 | 1.00 | PSMB5 (0.63) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| D-Leucine SCHEMBL2338392 | 1.00 | PSMB5 (0.63) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Leucine SCHEMBL2336540 | 1.00 | PSMB5 (0.63) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Leucine SCHEMBL1406108 | 0.97 | PSMB5 (0.66) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Leucine SCHEMBL19712512 | 0.97 | PSMB5 (0.66) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Leucine SCHEMBL28490857 | 0.94 | PSMB5 (0.68) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| Leucine SCHEMBL2931152 | 0.94 | PSMB5 (0.68) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL20496418 | 0.90 | PSMB5 (0.58) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL2344285 | 0.88 | PSMB5 (0.60) | PSMB5LONP1PSMB8PSMB9PSMB6 | |
| SCHEMBL2126381 | 0.87 | PSMB5 (0.72) | PSMB5LONP1PSMB8PSMB9PSMB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106636043-B | Method for producing protease | 广州立白企业集团有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-111925385-B | Synthesis of esters and acid compounds of boron | 千禧药品公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-108329337-B | Synthesis of boronic ester and acid compounds | 千禧药品公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-108096562-B | Application of 20S proteasome inhibitor in preparation of medicine for treating Japanese encephalitis virus infection | 武汉百药联科科技有限公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-111925385-A | Synthesis of boronic ester and acid compounds | 千禧药品公司 | 2020-11-13 | — | — | CN | disclosed |
| CN-111373246-A | Polymeric nanoparticles comprising bortezomib | 希成生物医药 | 2020-07-03 | — | — | CN | disclosed |
| CN-107998400-B | Pharmaceutical composition and application thereof in preparation of drugs for treating flavivirus infection | 武汉百药联科科技有限公司 | 2020-06-02 | — | — | CN | disclosed |
| US-20200157143-A1 | SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS | MILLENNIUM PHARM INC (US) | 2020-05-21 | — | — | US | disclosed |
| CN-106636043-B | Method for producing protease | 广州立白企业集团有限公司 | 2020-04-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157143-A1 | SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS | BTD, BCL6, BRAP | PSMB5 17/4885LONP1 2151/4885PSMB8 43/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.