SCHEMBL21955441

SCHEMBL21955441

CC(C)[C@H](NC(=O)[C@@H]1CCCN1)C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 1/20 0.47
PRCP P42785 2/20 0.42
NOS2 P35228 2/20 0.41
NOS3 P29474 1/20 0.41
NOS1 P29475 1/20 0.41
CTSC P53634 3/20 0.40
CYP3A4 P08684 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40
CYP2C9 P11712 1/20 0.37
TSHR P16473 1/20 0.37
TLR2 O60603 1/20 0.36
DDOST P39656 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25728331 1.00 DPP7 (0.47) DPP7PRCPNOS2NOS3NOS1
SCHEMBL30866235 1.00 DPP7 (0.47) DPP7PRCPNOS2NOS3NOS1
SCHEMBL19258205 0.89 DPP7 (0.46) DPP7PRCPNOS2NOS3NOS1
SCHEMBL19138319 0.89 DPP7 (0.46) DPP7PRCPNOS2NOS3NOS1
SCHEMBL17469367 0.89 DPP7 (0.46) DPP7PRCPNOS2NOS3NOS1
SCHEMBL17469380 0.89 DPP7 (0.46) DPP7PRCPNOS2NOS3NOS1
Hydrochloric Acid SCHEMBL28600561 0.88 DPP7 (0.45) DPP7PRCPNOS2NOS3NOS1
Hydrochloric Acid SCHEMBL28600562 0.88 DPP7 (0.45) DPP7PRCPNOS2NOS3NOS1
Hydrochloric Acid SCHEMBL28600564 0.88 DPP7 (0.45) DPP7PRCPNOS2NOS3NOS1
SCHEMBL16853543 0.87 DPP7 (0.49) DPP7PRCPCTSCCYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11622994-B2 Therapy for vitiligo CLINUVEL PHARMACEUTICALS LIMITED (AU) 2023-04-11 US claimed
CN-114292312-A Method for synthesizing 9 peptide-1 in full liquid phase 湖南微肽生物医药有限公司 2022-04-08 CN claimed
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS ENDEVICA BIO INC (US) 2026-04-09 US disclosed
EP-4605407-A2 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS Endevica Bio, Inc. (US) 2025-08-27 EP disclosed
WO-2025123055-A1 NON-NATURALLY OCCURRING MELANOCORTIN ANALOGS AND ASSOCIATED METHODS FOR MODULATING WEIGHT GAIN ENDEVICA BIO, INC. (US) 2025-06-12 WO disclosed
WO-2024086381-A2 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS ENDEVICA BIO, INC. (US) 2024-04-25 WO disclosed
US-11622994-B2 Therapy for vitiligo CLINUVEL PHARMACEUTICALS LIMITED (AU) 2023-04-11 US disclosed
US-11332499-B2 Cyclic peptides and methods of use thereof REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2022-05-17 US disclosed
CN-114292312-A Method for synthesizing 9 peptide-1 in full liquid phase 湖南微肽生物医药有限公司 2022-04-08 CN disclosed
US-10919937-B2 Bicyclic peptide ligands and uses thereof BICYCLETX LIMITED (GB) 2021-02-16 US disclosed
US-20200131228-A1 BICYCLIC PEPTIDE LIGANDS AND USES THEREOF BICYCLETX LIMITED (GB) 2020-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11332499-B2 Cyclic peptides and methods of use thereof ANPEP, NPR3, XPNPEP1 DPP7 316/4885PRCP 176/4885NOS2 1582/4885
US-20260098072-A1 METHODS OF STIMULATING APPETITE AND/OR INCREASING BODY WEIGHT USING NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR ANTAGONIST ANALOGS MC1R, MC4R, MC5R DPP7 155/4885PRCP 706/4885NOS2 956/4885
US-20200131228-A1 BICYCLIC PEPTIDE LIGANDS AND USES THEREOF VIP, NGLY1, BID DPP7 109/4885PRCP 191/4885NOS2 3907/4885
US-11622994-B2 Therapy for vitiligo MC1R, MC3R, MC5R DPP7 2268/4885PRCP 704/4885NOS2 3285/4885
US-10919937-B2 Bicyclic peptide ligands and uses thereof VIP, NGLY1, BID DPP7 109/4885PRCP 191/4885NOS2 3907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.