Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21958395 | 0.95 | JAK1 (0.61) | JAK1JAK2 | |
| SCHEMBL28596869 | 0.83 | JAK1 (0.69) | JAK1JAK2 | |
| SCHEMBL28608389 | 0.83 | JAK1 (0.69) | JAK1JAK2 | |
| SCHEMBL30173344 | 0.83 | JAK1 (0.69) | JAK1JAK2 | |
| SCHEMBL30173275 | 0.83 | JAK1 (0.69) | JAK1JAK2 | |
| SCHEMBL28603790 | 0.83 | JAK1 (0.72) | JAK1JAK2 | |
| SCHEMBL30173268 | 0.83 | JAK1 (0.72) | JAK1JAK2 | |
| SCHEMBL21958406 | 0.81 | JAK1 (0.53) | JAK1JAK2 | |
| SCHEMBL28611293 | 0.81 | JAK1 (0.65) | JAK1JAK2 | |
| SCHEMBL30173317 | 0.81 | JAK1 (0.65) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020081689-A1 | AZAINDOLE INHIBITORS OF WILD-TYPE AND MUTANT FORMS OF LRRK2 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-04-23 | — | — | WO | disclosed |