Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 6/20 | 0.53 |
| ▸ | JUN | P05412 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.53 |
| ▸ | RELA | Q04206 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17448400 | 0.90 | P2RX1 (0.63) | P2RX1JUNNFKB1NFKB2RELA | |
| SCHEMBL21959841 | 0.85 | P2RX1 (0.60) | P2RX1JUNNFKB1NFKB2RELA | |
| SCHEMBL21937530 | 0.84 | P2RX1 (0.56) | P2RX1JUNNFKB1NFKB2RELA | |
| SCHEMBL26786131 | 0.84 | JUN (0.59) | P2RX1JUNNFKB1NFKB2RELA | |
| SCHEMBL31677649 | 0.82 | TLR7 (0.61) | CYP1A2P2RX1JUNNFKB1NFKB2 | |
| SCHEMBL13561074 | 0.80 | KMT2A (0.72) | MAPTRAB9AALDH1A1TSHRP2RX1 | |
| SCHEMBL15832435 | 0.78 | MAPT (0.56) | MAPTSMN1; SMN2CYP1A2KDM4EALDH1A1 | |
| SCHEMBL31677612 | 0.77 | ACKR3 (0.50) | CYP1A2HPGDP2RX1JUNNFKB1 | |
| SCHEMBL26786944 | 0.77 | ACKR3 (0.50) | CYP1A2HPGDP2RX1JUNNFKB1 | |
| SCHEMBL17448401 | 0.77 | POLB (0.64) | MAPTNPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10858383-B2 | Remote heteroaryl alkenylation with catalytic bifunctional template | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-08 | — | — | US | disclosed |
| US-20200131213-A1 | Remote Heteroaryl Alkenylation With Catalytic Bifunctional Template | THE SCRIPPS RESEARCH INSTITUTE | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131213-A1 | Remote Heteroaryl Alkenylation With Catalytic Bifunctional Template | APEH, ALKBH3, JMJD7 | MAPT 2812/4885NPC1 4290/4885RAB9A 3246/4885 |
| US-10858383-B2 | Remote heteroaryl alkenylation with catalytic bifunctional template | APEH, ALKBH3, JMJD7 | MAPT 2812/4885NPC1 4290/4885RAB9A 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.