Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16914815 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3865730 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL5974304 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3859032 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3868800 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL16914892 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL5974299 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL21596745 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3865732 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3868799 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478675-B1 | HETEROAROMATIC DERIVATIVES AS NIK INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-22 | — | — | EP | disclosed |