Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 13/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959200 | 0.81 | GCK (0.51) | GCKRIPK1 | |
| SCHEMBL1960655 | 0.80 | GCK (0.52) | GCK | |
| SCHEMBL12490119 | 0.78 | GCK (0.46) | GCKRIPK1 | |
| SCHEMBL2195791 | 0.78 | GCK (0.44) | GCKDAORIPK1MET | |
| SCHEMBL1962013 | 0.77 | GCK (0.75) | GCK | |
| SCHEMBL2199152 | 0.76 | GCK (0.73) | GCK | |
| SCHEMBL2197752 | 0.74 | GCK (0.40) | GCK | |
| SCHEMBL1964350 | 0.74 | GCK (0.63) | GCK | |
| SCHEMBL1961224 | 0.74 | GCK (0.63) | GCK | |
| SCHEMBL29460593 | 0.73 | DAO (0.50) | GCKDAORIPK1HRH4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011080755-A1 | FUSED NITROGEN HETEROCYCLIC COMPOUNDS, PROCESS OF PREPARATION AND USES THEREOF | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2011-07-07 | — | — | WO | disclosed |