Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678624 | 0.80 | DPP4 (0.33) | DPP4DPP7 | |
| SCHEMBL910644 | 0.78 | DPP4 (0.36) | DPP4DPP7 | |
| SCHEMBL28244513 | 0.78 | DPP4 (0.33) | DPP4DPP7 | |
| SCHEMBL24435063 | 0.77 | DPP4 (0.32) | DPP4DPP7 | |
| SCHEMBL19401359 | 0.77 | DPP4 (0.32) | DPP4DPP7 | |
| SCHEMBL14270060 | 0.75 | DPP4 (0.40) | DPP4DPP7 | |
| SCHEMBL7984091 | 0.75 | ALDH1A1 (0.36) | ALDH1A1ALOX15 | |
| SCHEMBL7990091 | 0.75 | ALDH1A1 (0.36) | ALDH1A1ALOX15 | |
| SCHEMBL7990097 | 0.75 | ALDH1A1 (0.36) | ALDH1A1ALOX15 | |
| SCHEMBL5482843 | 0.75 | DPP4 (0.40) | DPP4DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131201-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131201-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK2, JAK1 | DPP4 3765/4885DPP7 2864/4885ALDH1A1 4827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.