Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196582 | 0.99 | CNR1 (0.36) | CNR1CNR2HPGDUSP2HSD17B10 | |
| SCHEMBL2195778 | 0.91 | CNR2 (0.41) | CNR1CNR2HPGDUSP2HSD17B10 | |
| SCHEMBL2195352 | 0.91 | CNR2 (0.41) | CNR1CNR2HPGDUSP2HSD17B10 | |
| SCHEMBL2195510 | 0.90 | CNR1 (0.39) | CNR1CNR2HPGDUSP2HSD17B10 | |
| SCHEMBL2195569 | 0.88 | CNR1 (0.37) | CNR1CNR2HPGDALDH1A1KDM4E | |
| SCHEMBL2194293 | 0.86 | MAPT (0.39) | CNR1CNR2ALDH1A1 | |
| SCHEMBL2192592 | 0.86 | MAPT (0.39) | CNR1CNR2ALDH1A1 | |
| SCHEMBL2194637 | 0.86 | KDM4E (0.40) | ALDH1A1KDM4EBACE1 | |
| SCHEMBL2196211 | 0.86 | KDM4E (0.40) | ALDH1A1KDM4EBACE1 | |
| SCHEMBL2195092 | 0.84 | MAPT (0.47) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040513-B2 | Process for preparing platinum-carbene complexes | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-05-26 | — | — | US | disclosed |
| US-8980875-B2 | Platinum-N-heterocyclic carbene derivatives, preparation thereof and therapeutic use thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-03-17 | — | — | US | disclosed |
| US-20140058061-A1 | PROCESS FOR PREPARING PLATINUM-CARBENE COMPLEXES | ULNIVERSITE DE STRASBOUGE (FR) | 2014-02-27 | — | — | US | disclosed |
| US-20130338128-A1 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2013-12-19 | — | — | US | disclosed |
| US-8481522-B2 | Platinum-N-heterocyclic carbene derivatives, preparation thereof and therapeutic use thereof | SANOFI (FR) | 2013-07-09 | — | — | US | disclosed |
| US-20110172199-A1 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140058061-A1 | PROCESS FOR PREPARING PLATINUM-CARBENE COMPLEXES | PMS2, PCBP1, PARG | CNR1 3870/4885CNR2 4158/4885HPGD 1568/4885 |
| US-20130338128-A1 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SCO2, C3AR1, IDH1 | CNR1 278/4885CNR2 203/4885HPGD 1468/4885 |
| US-20110172199-A1 | PLATINUM-N-HETEROCYCLIC CARBENE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SCO2, C3AR1, IDH1 | CNR1 278/4885CNR2 203/4885HPGD 1468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.