Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21963872 | 0.93 | ADM2 (0.64) | ADM2CALCB | |
| SCHEMBL22014162 | 0.92 | CALCB (0.64) | ADM2CALCB | |
| SCHEMBL22014164 | 0.91 | CALCB (0.75) | ADM2CALCB | |
| SCHEMBL29368686 | 0.91 | CALCB (0.75) | ADM2CALCB | |
| SCHEMBL22014481 | 0.91 | CALCB (0.75) | ADM2CALCB | |
| SCHEMBL21963904 | 0.87 | ADM2 (0.61) | ADM2CALCB | |
| SCHEMBL21963866 | 0.87 | ADM2 (0.57) | ADM2CALCB | |
| SCHEMBL24962198 | 0.87 | ADM2 (0.61) | ADM2CALCB | |
| SCHEMBL23257340 | 0.86 | ADM2 (0.81) | ADM2CALCB | |
| SCHEMBL29814087 | 0.86 | ADM2 (0.81) | ADM2CALCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880308-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | The University Of Sheffield (GB) | 2021-09-22 | — | — | EP | disclosed |
| WO-2020099885-A1 | HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS | THE UNIVERSITY OF SHEFFIELD (GB) | 2020-05-22 | — | — | WO | disclosed |