Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183233 | 0.82 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL23880174 | 0.77 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL1559603 | 0.75 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL28125498 | 0.75 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL7686440 | 0.73 | SMN1; SMN2 (0.44) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL18418903 | 0.72 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL18049571 | 0.72 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL18049623 | 0.72 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL18418878 | 0.69 | MAPT (0.44) | L3MBTL1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL21960914 | 0.68 | SMN1; SMN2 (0.42) | L3MBTL1ALDH1A1MAPTPOLBCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478675-B1 | HETEROAROMATIC DERIVATIVES AS NIK INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-22 | — | — | EP | disclosed |