Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | EPN1 | Q9Y6I3 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21961444 | 0.76 | BAZ2B (0.39) | HCAR2DAOMAPK1 | |
| SCHEMBL22939364 | 0.72 | — | — | |
| SCHEMBL1245535 | 0.72 | MAPK1 (0.47) | HCAR2DAOMAPK1CYTH3BTK | |
| SCHEMBL4420054 | 0.71 | — | — | |
| SCHEMBL21960941 | 0.69 | NPC1 (0.38) | HCAR2 | |
| SCHEMBL11215462 | 0.67 | KMT2A (0.46) | HCAR2DAO | |
| SCHEMBL3053796 | 0.67 | ALOX15 (0.51) | MAPK1 | |
| SCHEMBL18464503 | 0.66 | — | — | |
| SCHEMBL28155997 | 0.66 | — | — | |
| SCHEMBL5013388 | 0.65 | HPGD (0.52) | HCAR2DAOMAPK1CYTH3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478675-B1 | HETEROAROMATIC DERIVATIVES AS NIK INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-04-22 | — | — | EP | disclosed |