Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 3/20 | 0.32 |
| ▸ | DNM2 | P50570 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788846 | 0.73 | ABL1 (0.47) | ABL1KCNH3ALDH1A1ADRA2A | |
| SCHEMBL1241959 | 0.71 | ABL1 (0.56) | ABL1KCNH3ALDH1A1ADRA2ALMNA | |
| SCHEMBL2196495 | 0.71 | ABL1 (0.44) | ABL1KCNH3CNR2ALDH1A1ADRA2A | |
| SCHEMBL16439908 | 0.69 | ABL1 (0.59) | ABL1KCNH3ALDH1A1ADRA2APLK1 | |
| SCHEMBL187892 | 0.69 | ABL1 (0.59) | ABL1KCNH3ALDH1A1ADRA2APLK1 | |
| SCHEMBL2720066 | 0.69 | ABL1 (0.59) | ABL1KCNH3ALDH1A1ADRA2APLK1 | |
| SCHEMBL11498100 | 0.69 | ABL1 (0.59) | ABL1KCNH3ALDH1A1ADRA2APLK1 | |
| SCHEMBL9506930 | 0.69 | ABL1 (0.59) | ABL1KCNH3ALDH1A1ADRA2APLK1 | |
| SCHEMBL11476522 | 0.69 | ABL1 (0.59) | ABL1KCNH3ALDH1A1ADRA2APLK1 | |
| SCHEMBL3395174 | 0.69 | ABL1 (0.59) | ABL1KCNH3ALDH1A1ADRA2APLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289000-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2013-10-31 | — | — | US | disclosed |
| US-8470803-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| EP-2348863-A1 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| US-20110166103-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-07-07 | — | — | US | disclosed |
| WO-2010027975-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166103-A1 | BORON-CONTAINING SMALL MOLECULES | NFKBIA, BCL6B, TNF | ABL1 287/4885KCNH3 4583/4885CNR2 1024/4885 |
| US-20130289000-A1 | BORON-CONTAINING SMALL MOLECULES | NFKBIA, BCL6B, TNF | ABL1 287/4885KCNH3 4583/4885CNR2 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.