Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PLK1 | P53350 | 3/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788846 | 0.76 | ABL1 (0.47) | ABL1KCNH3ALDH1A1EPHX1ADRA2A | |
| SCHEMBL28158771 | 0.71 | ALDH1A1 (0.56) | ABL1ALDH1A1ACHE | |
| SCHEMBL8589161 | 0.71 | EPHX1 (0.60) | ABL1KCNH3ALDH1A1EPHX1CNR2 | |
| SCHEMBL1241959 | 0.71 | ABL1 (0.56) | ABL1KCNH3ALDH1A1ADRA2AACHE | |
| SCHEMBL2196500 | 0.71 | ABL1 (0.44) | ABL1KCNH3ALDH1A1ADRA2ACNR2 | |
| SCHEMBL10583953 | 0.70 | EPHX1 (0.62) | ABL1KCNH3ALDH1A1EPHX1CNR2 | |
| SCHEMBL12260011 | 0.70 | ABL1 (0.54) | ABL1KCNH3ALDH1A1EPHX1ADRA2A | |
| SCHEMBL12260009 | 0.70 | ABL1 (0.54) | ABL1KCNH3ALDH1A1EPHX1ADRA2A | |
| SCHEMBL11683978 | 0.70 | EPHX1 (0.62) | ABL1KCNH3ALDH1A1EPHX1CNR2 | |
| SCHEMBL11683181 | 0.70 | EPHX1 (0.62) | ABL1KCNH3ALDH1A1EPHX1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130289000-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS INC (US) | 2013-10-31 | — | — | US | disclosed |
| US-8470803-B2 | Boron-containing small molecules | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| EP-2348863-A1 | BORON-CONTAINING SMALL MOLECULES | Anacor Pharmaceuticals, Inc. (US) | 2011-08-03 | — | — | EP | disclosed |
| US-20110166103-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-07-07 | — | — | US | disclosed |
| WO-2010027975-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2010-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166103-A1 | BORON-CONTAINING SMALL MOLECULES | NFKBIA, BCL6B, TNF | ABL1 287/4885KCNH3 4583/4885ALDH1A1 4038/4885 |
| US-20130289000-A1 | BORON-CONTAINING SMALL MOLECULES | NFKBIA, BCL6B, TNF | ABL1 287/4885KCNH3 4583/4885ALDH1A1 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.