Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 10/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21872995 | 0.79 | CSF1R (0.48) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL21965142 | 0.71 | CSF1R (0.42) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL21873156 | 0.71 | CSF1R (0.52) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL21965088 | 0.69 | CSF1R (0.42) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL21965026 | 0.68 | CSF1R (0.41) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL21873140 | 0.66 | GPR84 (0.46) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL21873148 | 0.63 | CSF1R (0.44) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL21977192 | 0.63 | CSF1R (0.43) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL21873024 | 0.62 | CSF1R (0.44) | CSF1RPDGFRAPDGFRBKDRFLT3 | |
| SCHEMBL16049194 | 0.61 | CSF1R (1.00) | CSF1RPDGFRAPDGFRBKDRFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643715-A1 | NITROGEN HETEROARYL DERIVATIVE HAVING CSF1R INHIBITORY ACTIVITY, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2020-04-29 | — | — | EP | disclosed |