SCHEMBL21965375

SCHEMBL21965375

O=C1CCC(Nc2cccc(Cl)c2)C(=O)N1

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 19/20 0.72
CRBN Q96SW2 19/20 0.72
FADS1 O60427 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26328213 0.86 DDB1 (0.54) DDB1CRBNFADS1
SCHEMBL22117653 0.84 CRBN (1.00) DDB1CRBN
SCHEMBL22117604 0.84 CRBN (1.00) DDB1CRBN
SCHEMBL22117787 0.84 CRBN (1.00) DDB1CRBN
SCHEMBL24290121 0.83 DDB1 (0.72) DDB1CRBN
Hydrochloric Acid SCHEMBL22117857 0.83 CRBN (0.97) DDB1CRBN
SCHEMBL21965746 0.83 DDB1 (0.72) DDB1CRBN
Bromide SCHEMBL22128737 0.83 CRBN (0.97) DDB1CRBN
SCHEMBL30936762 0.83 DDB1 (0.72) DDB1CRBN
SCHEMBL21965932 0.83 DDB1 (0.72) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219606-A Substituted 3- ((3-aminophenyl) amino) piperidine-2, 6-dione compounds, compositions thereof, and methods of treatment using the same 细胞基因公司 2024-12-31 CN disclosed
US-20230279023-A1 N/O-Linked Degrons and Degronimers for Protein Degradation C4 THERAPEUTICS, INC. (US) 2023-09-07 US disclosed
US-20200140456-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION C4 THERAPEUTICS, INC. (US) 2020-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230279023-A1 N/O-Linked Degrons and Degronimers for Protein Degradation CRBN, CBL, STUB1 DDB1 319/4885CRBN 1/4885FADS1 3229/4885
US-20200140456-A1 N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION CRBN, CBL, STUB1 DDB1 319/4885CRBN 1/4885FADS1 3229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.