Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.69 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.69 |
| ▸ | KIF11 | P52732 | 3/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21965748 | 0.86 | DDB1 (0.69) | DDB1CRBNKIF11 | |
| SCHEMBL21965844 | 0.85 | DDB1 (0.71) | DDB1CRBNKIF11 | |
| SCHEMBL21965932 | 0.83 | DDB1 (0.72) | DDB1CRBNGRM5 | |
| SCHEMBL22117653 | 0.82 | CRBN (1.00) | DDB1CRBN | |
| SCHEMBL22117604 | 0.82 | CRBN (1.00) | DDB1CRBN | |
| SCHEMBL22117787 | 0.82 | CRBN (1.00) | DDB1CRBN | |
| SCHEMBL24290121 | 0.81 | DDB1 (0.72) | DDB1CRBN | |
| Bromide SCHEMBL22128737 | 0.81 | CRBN (0.97) | DDB1CRBN | |
| Hydrochloric Acid SCHEMBL22117857 | 0.81 | CRBN (0.97) | DDB1CRBN | |
| SCHEMBL21965746 | 0.81 | DDB1 (0.72) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | C4 THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | US | disclosed |
| US-20200140456-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230279023-A1 | N/O-Linked Degrons and Degronimers for Protein Degradation | CRBN, CBL, STUB1 | DDB1 319/4885CRBN 1/4885KIF11 964/4885 |
| US-20200140456-A1 | N/O-LINKED DEGRONS AND DEGRONIMERS FOR PROTEIN DEGRADATION | CRBN, CBL, STUB1 | DDB1 319/4885CRBN 1/4885KIF11 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.