Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 3/20 | 0.38 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 3/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29592454 | 0.84 | EGFR (0.39) | SYKVNN1PDPK1CHRNA7NAMPT | |
| SCHEMBL14783097 | 0.84 | EGFR (0.39) | SYKVNN1PDPK1CHRNA7NAMPT | |
| SCHEMBL14783544 | 0.83 | EGFR (0.41) | PIK3CASYKALDH1A1CHRNA7 | |
| SCHEMBL14783305 | 0.83 | EGFR (0.38) | PIK3CASYKKDM4EALDH1A1POLB | |
| SCHEMBL28256066 | 0.83 | PIK3CA (0.38) | PIK3CASYKKDM4EALDH1A1POLB | |
| SCHEMBL29591362 | 0.81 | RAB9A (0.42) | POLBGAA | |
| SCHEMBL14783467 | 0.81 | RAB9A (0.42) | POLBGAA | |
| SCHEMBL14716098 | 0.76 | HDAC3 (0.46) | HSD17B14ALDH1A1POLBGAAHPGD | |
| SCHEMBL14783336 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1POLBGAAPDPK1 | |
| SCHEMBL29591616 | 0.76 | KDM4E (0.42) | KDM4EALDH1A1POLBGAAPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3332785-B1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA INC (US) | 2020-05-06 | — | — | EP | disclosed |