Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551920 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ERECQLGRIN1GRIN2B | |
| SCHEMBL24834896 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ERECQLGRIN1GRIN2B | |
| SCHEMBL2551922 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ERECQLGRIN1GRIN2B | |
| SCHEMBL5593707 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ERECQLGRIN1GRIN2B | |
| Water SCHEMBL27851978 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4ERECQLGRIN1GRIN2B | |
| SCHEMBL2683097 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4ERECQLGRIN1GRIN2B | |
| SCHEMBL14667519 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KDM4ERECQLGRIN1GRIN2B | |
| SCHEMBL14703128 | 0.77 | GRIN1 (0.49) | ALDH1A1GRIN1GRIN2BTSHRHIF1A | |
| SCHEMBL28775033 | 0.76 | GRIN1 (0.61) | ALDH1A1KDM4EGRIN1GRIN2BTSHR | |
| SCHEMBL3103042 | 0.74 | GRIN1 (0.50) | ALDH1A1GRIN1GRIN2BTSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2739289-B1 | GLYCOPEPTIDE ANTIBIOTIC ANALOGS EFFECTIVE AGAINST VANCOMYCIN-RESISTANT BACTERIAL STRAINS | SCRIPPS RESEARCH INST (US) | 2020-05-06 | — | — | EP | disclosed |