Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 7/20 | 0.60 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21967846 | 0.97 | FLT3 (0.56) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967400 | 0.93 | FLT3 (0.59) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967706 | 0.92 | FLT3 (0.72) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967801 | 0.92 | FLT3 (0.58) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967824 | 0.92 | FLT3 (0.58) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967315 | 0.91 | FLT3 (0.59) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967445 | 0.90 | FLT3 (0.64) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967831 | 0.90 | FLT3 (0.58) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967784 | 0.90 | FLT3 (0.58) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21967861 | 0.89 | FLT3 (0.55) | FLT3YTHDC1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662194-B2 | Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2020-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10662194-B2 | Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress | TPMT, MTAP, ATIC | FLT3 2877/4885YTHDC1 384/4885NPC1 3926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.