SCHEMBL2196991

SCHEMBL2196991

C=CC(=O)OC(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4848421 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL2199659 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL223954 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL2141800 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL7899865 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL14312167 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL4893018 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL347671 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL5087397 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL4885934 1.00 TSHR (0.35) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109422850-B Self-crosslinking fluorine-containing macromolecular emulsifier, fluorine-containing emulsion containing emulsifier, and preparation and use methods thereof 浙江大学 2021-07-02 CN claimed
CN-109400802-B Hydrophobic and oleophobic modifier and preparation method thereof, and preparation method of modified powder 中国科学技术大学 2020-12-25 CN claimed
CN-109180858-B Modifier, double-hydrophobic BC superfine dry powder extinguishing agent and preparation method thereof 中国科学技术大学 2020-01-31 CN claimed
CN-110038248-B Method for preparing anti-afterburning superfine dry powder extinguishing agent by using polymer sol 中国科学技术大学 2021-05-07 CN disclosed
CN-109400802-B Hydrophobic and oleophobic modifier and preparation method thereof, and preparation method of modified powder 中国科学技术大学 2020-12-25 CN disclosed
CN-109224362-B ABC type superfine dry powder extinguishing agent and preparation method thereof 中国科学技术大学 2020-08-28 CN disclosed
CN-109180858-B Modifier, double-hydrophobic BC superfine dry powder extinguishing agent and preparation method thereof 中国科学技术大学 2020-01-31 CN disclosed
US-20160186321-A1 TREATMENT OF FIBROUS MATERIALS USING ATMOSPHERIC PRESSURE PLASMA POLYMERIZATION APJET INC (US) 2016-06-30 US disclosed
US-9157191-B2 Treatment of fibrous materials using atmospheric pressure plasma polymerization APJET, INC. (US) 2015-10-13 US disclosed
EP-1831305-B1 GRAFT COPOLYMERS WITH SEGMENTED ARMS COATINGS FOREIGN IP CO LLC (US) 2015-08-12 EP disclosed
US-7976583-B2 Oil-, water- and soil-repellent perfluoroalkylethyl methacrylate copolymers CLARIANT FINANCE (BVI) LIMITED (VG) 2011-07-12 US disclosed
US-20090325849-A1 Oil-, Water- And Soil-Repellent Perfluoroalkylethyl Methacrylate Copolymers CLARIANT FINANCE (BVI) LIMITED (VG) 2009-12-31 US disclosed
EP-2057201-B1 OIL-, WATER- AND SOIL-REPELLENT PERFLUOROALKYLETHYL METHACRYLATE COPOLYMERS CLARIANT FINANCE BVI LTD (VG) 2009-12-23 EP disclosed
EP-2057201-A1 OIL-, WATER- AND SOIL-REPELLENT PERFLUOROALKYLETHYL METHACRYLATE COPOLYMERS Clariant International Ltd. (CH) 2009-05-13 EP disclosed
US-7402624-B2 Graft copolymers with segmented arms and their preparation and use E.I. DU PONT DE NEMOURS & COMPANY (US) 2008-07-22 US disclosed
US-20080107822-A1 TREATMENT OF FIBROUS MATERIALS USING ATMOSPHERIC PRESSURE PLASMA POLYMERIZATION APJET, INC. (US) 2008-05-08 US disclosed
WO-2008022985-A1 OIL-, WATER- AND SOIL-REPELLENT PERFLUOROALKYLETHYL METHACRYLATE COPOLYMERS CLARIANT INTERNATIONAL LTD (CH) 2008-02-28 WO disclosed
EP-1831305-A2 GRAFT COPOLYMERS WITH SEGMENTED ARMS AND THEIR PREPARATION AND USE E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-09-12 EP disclosed
WO-2006052981-A2 GRAFT COPOLYMERS WITH SEGMENTED ARMS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-05-18 WO disclosed
US-20060100305-A1 Graft copolymers with segmented arms and their preparation and use AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2006-05-11 US disclosed