SCHEMBL4893018

SCHEMBL4893018

C=CC(=O)OC(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4848421 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL2199659 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL223954 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL2141800 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL7899865 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL14312167 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL347671 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL5087397 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL2196991 1.00 TSHR (0.35) TSHRTHRB
SCHEMBL4885934 1.00 TSHR (0.35) TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160186321-A1 TREATMENT OF FIBROUS MATERIALS USING ATMOSPHERIC PRESSURE PLASMA POLYMERIZATION APJET INC (US) 2016-06-30 US disclosed
US-9157191-B2 Treatment of fibrous materials using atmospheric pressure plasma polymerization APJET, INC. (US) 2015-10-13 US disclosed
US-20080107822-A1 TREATMENT OF FIBROUS MATERIALS USING ATMOSPHERIC PRESSURE PLASMA POLYMERIZATION APJET, INC. (US) 2008-05-08 US disclosed