SCHEMBL2196995

SCHEMBL2196995

C=CC(=O)OC(F)(C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28604185 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1
SCHEMBL28581309 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1
SCHEMBL2199662 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1
SCHEMBL675092 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1
SCHEMBL4893028 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1
SCHEMBL4848426 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1
SCHEMBL223955 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1
SCHEMBL14312168 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1
SCHEMBL4885942 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1
SCHEMBL826852 1.00 THRB (0.35) THRBALDH1A1TP53CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109422850-B Self-crosslinking fluorine-containing macromolecular emulsifier, fluorine-containing emulsion containing emulsifier, and preparation and use methods thereof 浙江大学 2021-07-02 CN claimed
CN-109400802-B Hydrophobic and oleophobic modifier and preparation method thereof, and preparation method of modified powder 中国科学技术大学 2020-12-25 CN claimed
CN-109180858-B Modifier, double-hydrophobic BC superfine dry powder extinguishing agent and preparation method thereof 中国科学技术大学 2020-01-31 CN claimed
CN-110038248-B Method for preparing anti-afterburning superfine dry powder extinguishing agent by using polymer sol 中国科学技术大学 2021-05-07 CN disclosed
CN-109400802-B Hydrophobic and oleophobic modifier and preparation method thereof, and preparation method of modified powder 中国科学技术大学 2020-12-25 CN disclosed
CN-109224362-B ABC type superfine dry powder extinguishing agent and preparation method thereof 中国科学技术大学 2020-08-28 CN disclosed
CN-109180858-B Modifier, double-hydrophobic BC superfine dry powder extinguishing agent and preparation method thereof 中国科学技术大学 2020-01-31 CN disclosed
US-20160186321-A1 TREATMENT OF FIBROUS MATERIALS USING ATMOSPHERIC PRESSURE PLASMA POLYMERIZATION APJET INC (US) 2016-06-30 US disclosed
US-9157191-B2 Treatment of fibrous materials using atmospheric pressure plasma polymerization APJET, INC. (US) 2015-10-13 US disclosed
US-7976583-B2 Oil-, water- and soil-repellent perfluoroalkylethyl methacrylate copolymers CLARIANT FINANCE (BVI) LIMITED (VG) 2011-07-12 US disclosed
US-20090325849-A1 Oil-, Water- And Soil-Repellent Perfluoroalkylethyl Methacrylate Copolymers CLARIANT FINANCE (BVI) LIMITED (VG) 2009-12-31 US disclosed
EP-2057201-B1 OIL-, WATER- AND SOIL-REPELLENT PERFLUOROALKYLETHYL METHACRYLATE COPOLYMERS CLARIANT FINANCE BVI LTD (VG) 2009-12-23 EP disclosed
EP-2057201-A1 OIL-, WATER- AND SOIL-REPELLENT PERFLUOROALKYLETHYL METHACRYLATE COPOLYMERS Clariant International Ltd. (CH) 2009-05-13 EP disclosed
US-20080107822-A1 TREATMENT OF FIBROUS MATERIALS USING ATMOSPHERIC PRESSURE PLASMA POLYMERIZATION APJET, INC. (US) 2008-05-08 US disclosed
WO-2008022985-A1 OIL-, WATER- AND SOIL-REPELLENT PERFLUOROALKYLETHYL METHACRYLATE COPOLYMERS CLARIANT INTERNATIONAL LTD (CH) 2008-02-28 WO disclosed