Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17559582 | 0.84 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL17559583 | 0.84 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL21970762 | 0.83 | POLB (0.41) | F10HCRTR1NPSR1HCRTR2ALDH1A1 | |
| SCHEMBL19435354 | 0.82 | HCRTR1 (0.43) | F10HCRTR1HCRTR2 | |
| SCHEMBL19435351 | 0.82 | HCRTR1 (0.43) | F10HCRTR1HCRTR2 | |
| SCHEMBL17559602 | 0.81 | F10 (0.43) | F10HCRTR1MAPK1HCRTR2TP53 | |
| SCHEMBL17559600 | 0.81 | F10 (0.43) | F10HCRTR1MAPK1HCRTR2TP53 | |
| SCHEMBL22679027 | 0.80 | F10 (0.36) | F10TSHRMAPK1NPSR1RAB9A | |
| SCHEMBL19435333 | 0.79 | TSHR (0.45) | TSHRMAPK1NPSR1RAB9ASMN1; SMN2 | |
| SCHEMBL17571402 | 0.77 | HCRTR1 (0.43) | HCRTR1TSHRMAPK1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442958-B1 | NOVEL N-[(PYRIDYLOXY)PROPANYL]BENZAMIDES | BOEHRINGER INGELHEIM INT (DE) | 2020-05-06 | — | — | EP | disclosed |