Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21970964 | 0.82 | POLB (0.42) | MME | |
| SCHEMBL6722464 | 0.68 | CYP2D6 (0.56) | MMELMNAHRH4HRH3TSHR | |
| SCHEMBL8436494 | 0.68 | TSHR (0.42) | HRH4HRH3TSHR | |
| SCHEMBL6722463 | 0.68 | HRH4 (0.43) | LMNAHRH4HRH3TSHR | |
| SCHEMBL25481755 | 0.68 | MEN1 (0.38) | MMETSHR | |
| SCHEMBL20103556 | 0.67 | CYP3A4 (0.37) | MME | |
| SCHEMBL21091583 | 0.66 | TSHR (0.41) | MMELMNAHRH4HRH3TSHR | |
| SCHEMBL6382972 | 0.66 | TSHR (0.41) | HRH4HRH3TSHR | |
| SCHEMBL8436493 | 0.66 | TSHR (0.41) | LMNAHRH4HRH3TSHR | |
| SCHEMBL25963585 | 0.66 | MEN1 (0.43) | HRH4HRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3270903-B1 | DISULFIDE-CONTAINING ALKYNE LINKING AGENTS | ARROWHEAD PHARMACEUTICALS INC (US) | 2020-05-06 | — | — | EP | disclosed |