Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21970634 | 0.85 | LMNA (0.59) | LMNAPDGFRBKDM4EMAPTDRD2 | |
| SCHEMBL21971004 | 0.85 | PDGFRB (0.53) | LMNAPDGFRBKDM4EMAPTTP53 | |
| SCHEMBL21971399 | 0.82 | LMNA (0.47) | LMNAPDGFRBHTR1AKDM4EMAPT | |
| SCHEMBL21972251 | 0.81 | LMNA (0.49) | LMNAPDGFRBKDM4EMAPTBRD4 | |
| SCHEMBL21972266 | 0.81 | LMNA (0.49) | LMNAPDGFRBHTR1AKDM4EMAPT | |
| SCHEMBL21972245 | 0.80 | LMNA (0.53) | LMNAHTR1AKDM4EMAPTDRD2 | |
| SCHEMBL21971408 | 0.80 | PDGFRB (0.47) | LMNAPDGFRBKDM4EMAPTTP53 | |
| SCHEMBL21972258 | 0.77 | LMNA (0.46) | LMNAPDGFRBKDM4EBRD4BRPF1 | |
| SCHEMBL20739825 | 0.77 | LMNA (0.54) | LMNAPDGFRBHTR1AKDM4EMAPT | |
| SCHEMBL21971007 | 0.76 | LMNA (0.49) | LMNAPDGFRBHTR1AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046655-B2 | Compound and method for producing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20200140394-A1 | NOVEL COMPOUND AND METHOD FOR PRODUCING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140394-A1 | NOVEL COMPOUND AND METHOD FOR PRODUCING SAME | CBR3, NR2E3, NR5A2 | LMNA 4733/4885PDGFRB 2517/4885HTR1A 1849/4885 |
| US-11046655-B2 | Compound and method for producing same | CBR3, NR5A1, NR2E3 | LMNA 4570/4885PDGFRB 2499/4885HTR1A 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.