Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | APP | P05067 | 3/20 | 0.32 |
| ▸ | SNCA | P37840 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21971400 | 0.87 | PDGFRB (0.58) | PDGFRBLMNAP2RX4HTTALDH1A1 | |
| SCHEMBL21970991 | 0.84 | PDGFRB (0.51) | PDGFRBLMNAP2RX4HTTALDH1A1 | |
| SCHEMBL20508364 | 0.81 | PDGFRB (0.53) | PDGFRBLMNAHTTALDH1A1KDM4E | |
| SCHEMBL21971403 | 0.80 | LMNA (0.63) | PDGFRBLMNAALDH1A1KDM4EGAA | |
| SCHEMBL21971001 | 0.80 | LMNA (0.51) | PDGFRBLMNAHTTALDH1A1KDM4E | |
| SCHEMBL21971009 | 0.77 | LMNA (0.63) | PDGFRBLMNAALDH1A1KDM4EGAA | |
| SCHEMBL20739438 | 0.77 | PDGFRB (0.57) | PDGFRBLMNAP2RX4HTTALDH1A1 | |
| SCHEMBL21970632 | 0.75 | PDGFRB (0.42) | PDGFRBLMNAHTTALDH1A1KDM4E | |
| SCHEMBL2498918 | 0.74 | PDGFRB (1.00) | PDGFRBLMNAHTTALDH1A1KDM4E | |
| SCHEMBL21971402 | 0.72 | PDGFRB (0.47) | PDGFRBLMNAHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11046655-B2 | Compound and method for producing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20200140394-A1 | NOVEL COMPOUND AND METHOD FOR PRODUCING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200140394-A1 | NOVEL COMPOUND AND METHOD FOR PRODUCING SAME | CBR3, NR2E3, NR5A2 | PDGFRB 2517/4885LMNA 4733/4885P2RX4 2712/4885 |
| US-11046655-B2 | Compound and method for producing same | CBR3, NR5A1, NR2E3 | PDGFRB 2499/4885LMNA 4570/4885P2RX4 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.