Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP4 | P49662 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424151 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKMT2ATHRB | |
| SCHEMBL10126832 | 0.84 | RECQL (0.41) | ALDH1A1LMNAMAPTKDM4EGAA | |
| SCHEMBL16305346 | 0.84 | RECQL (0.41) | ALDH1A1LMNAMAPTKDM4EGAA | |
| SCHEMBL4812720 | 0.81 | ALDH1A1 (0.64) | ALDH1A1LMNAMAPTKMT2ATHRB | |
| SCHEMBL2197225 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTKMT2ATHRB | |
| SCHEMBL12424147 | 0.80 | ALDH1A1 (0.49) | ALDH1A1LMNAMAPTKMT2ATHRB | |
| SCHEMBL13419591 | 0.79 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTKMT2ATHRB | |
| SCHEMBL16569962 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKMT2ATHRB | |
| SCHEMBL16569961 | 0.79 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTKMT2ATHRB | |
| SCHEMBL1047097 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977352-B2 | Triazolopyridine compounds useful for the treatment of degenerative and inflammatory diseases | GALAPAGOS NV (BE) | 2011-07-12 | — | — | US | disclosed |