⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1335595 | 0.83 | — | — | |
| SCHEMBL11206389 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL11207122 | 0.80 | ALDH1A1 (0.48) | — | |
| SCHEMBL6364430 | 0.75 | — | — | |
| SCHEMBL12158699 | 0.73 | — | — | |
| SCHEMBL11207382 | 0.71 | ALDH1A1 (0.52) | — | |
| SCHEMBL11207400 | 0.71 | ALDH1A1 (0.52) | — | |
| SCHEMBL6625852 | 0.71 | — | — | |
| SCHEMBL11256911 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL11256922 | 0.67 | ALDH1A1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796708-B2 | Pyrrolo [2,3-B] pyridine CDK9 kinase inhibitors | ABBVIE INC. (US) | 2017-10-24 | — | — | US | claimed |
| US-20160060257-A1 | PYRROLO [2,3-B] PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2016-03-03 | — | — | US | claimed |
| EP-2970278-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | AbbVie Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014139328-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2014-09-18 | — | — | WO | claimed |
| US-9796708-B2 | Pyrrolo [2,3-B] pyridine CDK9 kinase inhibitors | ABBVIE INC. (US) | 2017-10-24 | — | — | US | disclosed |
| WO-2016197900-A1 | PROCESS FOR PREPARING MESOTRIONE | ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) | 2016-12-15 | — | — | WO | disclosed |
| US-20160318897-A1 | AZOLE COMPOUNDS CARRYING AN IMINE-DERIVED SUBSTITUENT | BASF SE (DE) | 2016-11-03 | — | — | US | disclosed |
| EP-3083596-A1 | AZOLE COMPOUNDS CARRYING AN IMINE-DERIVED SUBSTITUENT | BASF SE (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-20160060257-A1 | PYRROLO [2,3-B] PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2016-03-03 | — | — | US | disclosed |
| EP-2970278-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | AbbVie Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2015091645-A1 | AZOLE COMPOUNDS CARRYING AN IMINE-DERIVED SUBSTITUENT | BASF SE (DE) | 2015-06-25 | — | — | WO | disclosed |
| WO-2014139328-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | ABBVIE INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| US-7034015-B2 | Interleukin 1 beta and tumour necrosis factor alpha inhibitors | LEO PHARMA A/S (DK) | 2006-04-25 | — | — | US | disclosed |
| US-20060058380-A1 | Novel aminobenzophenone compounds | OTTOSEN ERIK R | 2006-03-16 | — | — | US | disclosed |
| EP-1583735-A2 | NOVEL AMINOBENZOPHENONE COMPOUNDS | Leo Pharma A/S (DK) | 2005-10-12 | — | — | EP | disclosed |
| WO-2005009940-A1 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA A/S (DK) | 2005-02-03 | — | — | WO | disclosed |
| WO-2004056762-A2 | NOVEL AMINOBENZOPHENONE COMPOUNDS | LEO PHARMA A/S (DK) | 2004-07-08 | — | — | WO | disclosed |
| EP-1423356-A2 | NOVEL AMINOBENZOEPHENONES | Leo Pharma A/S (DK) | 2004-06-02 | — | — | EP | disclosed |
| US-20030119902-A1 | Interleukin 1 beta and tumour necrosis factor alpha inhibitors | LEO PHARMA A/S (DK) | 2003-06-26 | — | — | US | disclosed |
| WO-2003018535-A2 | NOVEL AMINOBENZOEPHENONES | LEO PHARMA A/S (DK) | 2003-03-06 | — | — | WO | disclosed |