Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 9/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | AHR | P35869 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GPR3 | P46089 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262221 | 0.94 | KIF11 (0.77) | KIF11MEN1KMT2ANPC1POLB | |
| SCHEMBL29563317 | 0.94 | KIF11 (0.77) | KIF11MEN1KMT2ANPC1POLB | |
| Carbazole SCHEMBL28016320 | 0.94 | KIF11 (0.77) | KIF11MEN1KMT2ANPC1POLB | |
| SCHEMBL19346259 | 0.86 | KIF11 (0.92) | KIF11MEN1KMT2ANPC1POLB | |
| SCHEMBL607346 | 0.86 | KIF11 (1.00) | KIF11MEN1KMT2ANPC1POLB | |
| SCHEMBL29406398 | 0.85 | AHR (0.85) | KIF11MEN1KMT2AAHRALDH1A1 | |
| SCHEMBL12219451 | 0.85 | AHR (0.85) | KIF11MEN1KMT2AAHRALDH1A1 | |
| SCHEMBL1636528 | 0.85 | AHR (0.85) | KIF11MEN1KMT2AAHRALDH1A1 | |
| SCHEMBL10141055 | 0.84 | KIF11 (0.75) | KIF11MEN1KMT2ANPC1POLB | |
| SCHEMBL29726991 | 0.84 | KIF11 (0.75) | KIF11MEN1KMT2ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3197982-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-05-06 | — | — | EP | disclosed |