Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200292 | 0.87 | MAPK14 (0.60) | MAPK14EPHX2HRH3 | |
| SCHEMBL12164732 | 0.83 | MAPK14 (0.59) | MAPK14EPHX2HRH3 | |
| SCHEMBL2196902 | 0.81 | MAPK14 (0.60) | MAPK14EPHX2 | |
| SCHEMBL2203135 | 0.81 | MAPK14 (0.57) | MAPK14EPHX2HRH3 | |
| SCHEMBL2197405 | 0.80 | MAPK14 (0.53) | MAPK14EPHX2SYKHRH3 | |
| SCHEMBL1964677 | 0.77 | MAPK14 (0.49) | MAPK14EPHX2 | |
| SCHEMBL15163136 | 0.77 | MAPK14 (0.50) | MAPK14EPHX2 | |
| SCHEMBL2201701 | 0.76 | MAPK14 (0.57) | MAPK14EPHX2 | |
| SCHEMBL1964681 | 0.75 | PPARG (0.47) | MAPK14EPHX2 | |
| SCHEMBL5751039 | 0.73 | MAPK14 (0.61) | MAPK14EPHX2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |