Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 2/20 | 0.41 |
| ▸ | INSR | P06213 | 2/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2197399 | 0.80 | MAPK14 (0.56) | MAPK14EPHX2SYKHRH3 | |
| SCHEMBL2200292 | 0.76 | MAPK14 (0.60) | MAPK14EPHX2HRH3 | |
| SCHEMBL2196902 | 0.74 | MAPK14 (0.60) | MAPK14EPHX2 | |
| SCHEMBL12164732 | 0.74 | MAPK14 (0.59) | MAPK14EPHX2HRH3 | |
| SCHEMBL30344808 | 0.73 | KDM4E (0.62) | NPC1ALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL2203135 | 0.72 | MAPK14 (0.57) | MAPK14EPHX2NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1911879 | 0.71 | NPC1 (0.69) | NPC1ALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL30344157 | 0.71 | NPC1 (0.59) | NPC1ALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL2201701 | 0.70 | MAPK14 (0.57) | MAPK14EPHX2NPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL259795 | 0.67 | NPC1 (0.77) | NPC1ALDH1A1SMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977387-B2 | Aminobenzophenone compounds | LEO PHARMA A/S (DK) | 2011-07-12 | — | — | US | disclosed |