Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.67 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.67 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171155 | 0.81 | ANPEP (0.50) | ANPEPENPEPCA1CA2CA9 | |
| SCHEMBL26547500 | 0.80 | ANPEP (0.75) | ANPEPENPEPGRM4CA1CA2 | |
| SCHEMBL9918246 | 0.79 | ANPEP (0.48) | ANPEPENPEPCA1CA2CA9 | |
| SCHEMBL7573702 | 0.79 | ANPEP (0.73) | ANPEPENPEPGRM4CA1CA2 | |
| SCHEMBL7616448 | 0.79 | ANPEP (0.73) | ANPEPENPEPGRM4CA1CA2 | |
| SCHEMBL7612693 | 0.79 | ANPEP (0.73) | ANPEPENPEPGRM4CA1CA2 | |
| SCHEMBL321516 | 0.79 | ANPEP (0.73) | ANPEPENPEPGRM4CA1CA2 | |
| SCHEMBL19592425 | 0.78 | ANPEP (0.47) | ANPEPENPEPGRM4CA1CA2 | |
| SCHEMBL22690103 | 0.78 | ANPEP (0.71) | ANPEPENPEPGRM4CA1CA2 | |
| SCHEMBL22691505 | 0.78 | ANPEP (0.71) | ANPEPENPEPGRM4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343298-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2020-05-06 | — | — | EP | disclosed |