Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19592282 | 0.86 | HDAC8 (0.45) | KMT2AHSD17B10CYP1A2HIF1A | |
| SCHEMBL19592278 | 0.85 | LOXL2 (0.43) | ALDH1A1KMT2AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL171155 | 0.81 | ANPEP (0.50) | ANPEPENPEPALDH1A1KMT2AHPGD | |
| SCHEMBL19592388 | 0.80 | TERT (0.43) | KMT2AHSD17B10CYP1A2SMN1; SMN2KDM4E | |
| SCHEMBL9918246 | 0.78 | ANPEP (0.48) | ANPEPENPEPALDH1A1KMT2AHPGD | |
| SCHEMBL19592272 | 0.78 | L3MBTL1 (0.52) | ALDH1A1KMT2AHPGDSMN1; SMN2RECQL | |
| SCHEMBL21974404 | 0.78 | ANPEP (0.67) | ANPEPENPEPALDH1A1KMT2ACA12 | |
| SCHEMBL19592361 | 0.77 | ALDH1A1 (0.47) | ALDH1A1KMT2AHSD17B10CYP1A2AKR1C3 | |
| SCHEMBL24767350 | 0.76 | GLA (0.38) | GRM4 | |
| SCHEMBL19592381 | 0.76 | PNP (0.37) | ALDH1A1KMT2AHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9814722-B2 | Heteroaryl substituted pyrrolo[2,3-B] pyridines and pyrrolo[2,3-B] pyrimidines as janus kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2017-11-14 | — | — | US | disclosed |