Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 9/20 | 0.44 |
| ▸ | NCF1 | P14598 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403471 | 0.88 | MAPT (0.54) | MAPTSMN1; SMN2KDM4ENPC1XBP1 | |
| SCHEMBL483802 | 0.87 | MAPT (0.55) | MAPTSMN1; SMN2KDM4ENPC1XBP1 | |
| SCHEMBL21974441 | 0.81 | APP (0.50) | MAPTMIFNCF1 | |
| SCHEMBL21974470 | 0.81 | MAPT (0.65) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL484006 | 0.81 | MAPT (0.45) | MAPTSMN1; SMN2KDM4ENPC1XBP1 | |
| SCHEMBL12403478 | 0.79 | MIF (0.52) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL13127319 | 0.77 | MAPT (0.53) | MAPTSMN1; SMN2KDM4ENPC1XBP1 | |
| SCHEMBL483920 | 0.77 | MAPT (0.56) | MAPTSMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL5957021 | 0.75 | MAPT (0.66) | MAPTSMN1; SMN2KDM4ENPC1XBP1 | |
| SCHEMBL15386063 | 0.73 | DRD2 (0.48) | MAPTSMN1; SMN2KDM4ENPC1XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411057-B1 | IMAGING AGENTS FOR DETECTING NEUROLOGICAL DISORDERS | LILLY CO ELI (US) | 2020-05-06 | — | — | EP | disclosed |